Exchange 2010: Unable to open Exchange Management Console – Initialization Failed

1. Close all MMC/EMC Instances before proceeding.
2. Open Powershell or Powershell IDE as the user you run the EMC under and execute the following command:.
3. Remove-ItemProperty -Path HKCU:\Software\Microsoft\ExchangeServer\v14\AdminTools\ -Name NodeStructureSettings
4. Close Powershell